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BOSTON – The state's unemployment rate trended slightly downward for November, according to the U.S. Bureau of Labor Statistics.

But for the first time in some years, it's shifted above the national unemployment rate.

The seasonally adjusted statewide November unemployment rate, released on Dec. 19, was 7.1 percent, down 0.1 of a percentage point over the month and up 0.4 of a percentage point over the year. The statewide seasonally adjusted jobs estimate showed a 6,500-job gain in November following a revised gain of 9,400 jobs in October.

The preliminary estimates put the unadjusted unemployment rate at 6.6 percent, down 0.2 of a percentage point over the

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PITTSFIELD, Mass. — A new biotechnology firm, Molecular Metabolism LLC, born out of a relationship with Nuclea Biotechnologies, has chosen Pittsfield as its  headquarters.

Molecular Metabolism is in the process of assembling its management team and is expected to create seven to 10 new jobs locally.

It is a development stage company focused on the discovery of biomarkers and therapeutic-based targets for metabolic syndromes and central nervous system (CNS) diseases. These biomarkers can aid physicians in determining the best, individualized courses of treatment for patients suffering from metabolic conditions, such as obesity, fatty liver disease and

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